Optimal evaluation of re-opening policies for COVID-19 through the use of metaheuristic schemes.

A new contagious disease or unidentified COVID-19 variants could provoke a new collapse in the global economy. Under such conditions, companies, factories, and organizations must adopt reopening policies that allow their operations to reduce economic effects. Effective reopening policies should be designed using mathematical models that emulate infection chains through individual interactions. In contrast to other modeling approaches, agent-based schemes represent a computational paradigm used to characterize the person-to-person interactions of individuals inside a system, providing accurate simulation results. To evaluate the optimal conditions for a reopening policy, authorities and decision-makers need to conduct an extensive number of simulations manually, with a high possibility of losing information and important details. For this reason, the integration of optimization and simulation of reopening policies could automatically find the realistic scenario under which the lowest risk of infection was attained. In this paper, the metaheuristic technique of the Whale Optimization Algorithm is used to find the solution with the minimal transmission risk produced by an agent-based model that emulates a hypothetical re-opening context. Our scheme finds the optimal results of different generical activation scenarios. The experimental results indicate that our approach delivers practical knowledge and essential estimations for identifying optimal re-opening strategies with the lowest transmission risk.

Monkeypox detection from skin lesion images using an amalgamation of CNN models aided with Beta function-based normalization scheme.

We have recently been witnessing that our society is starting to heal from the impacts of COVID-19. The economic, social and cultural impacts of a pandemic cannot be ignored and we should be properly equipped to deal with similar situations in future. Recently, Monkeypox has been concerning the international health community with its lethal impacts for a probable pandemic. In such situations, having appropriate protocols and methodologies to deal with the outbreak efficiently is of paramount interest to the world. Early diagnosis and treatment stand as the only viable option to tackle such problems. To this end, in this paper, we propose an ensemble learning-based framework to detect the presence of the Monkeypox virus from skin lesion images. We first consider three pre-trained base learners, namely Inception V3, Xception and DenseNet169 to fine-tune on a target Monkeypox dataset. Further, we extract probabilities from these deep models to feed into the ensemble framework. To combine the outcomes, we propose a Beta function-based normalization scheme of probabilities to learn an efficient aggregation of complementary information obtained from the base learners followed by the sum rule-based ensemble. The framework is extensively evaluated on a publicly available Monkeypox skin lesion dataset using a five-fold cross-validation setup to evaluate its effectiveness. The model achieves an average of 93.39%, 88.91%, 96.78% and 92.35% accuracy, precision, recall and F1 scores, respectively. The supporting source codes are presented in https://github.com/BihanBanerjee/MonkeyPox.

A two-tier feature selection method using Coalition game and Nystrom sampling for screening COVID-19 from chest X-Ray images.

The world is still under the threat of different strains of the coronavirus and the pandemic situation is far from over. The method, that is widely used for the detection of COVID-19 is Reverse Transcription Polymerase chain reaction (RT-PCR), which is a time-consuming method and is prone to manual errors, and has poor precision. Although many nations across the globe have begun the mass immunization procedure, the COVID-19 vaccine will take a long time to reach everyone. The application of artificial intelligence (AI) and computer-aided diagnosis (CAD) has been used in the domain of medical imaging for a long period. It is quite evident that the use of CAD in the detection of COVID-19 is inevitable. The main objective of this paper is to use convolutional neural network (CNN) and a novel feature selection technique to analyze Chest X-Ray (CXR) images for the detection of COVID-19. We propose a novel two-tier feature selection method, which increases the accuracy of the overall classification model used for screening COVID-19 CXRs. Filter feature selection models are often more effective than wrapper methods as wrapper methods tend to be computationally more expensive and are not useful for large datasets dealing with a large number of features. However, most filter methods do not take into consideration how a group of features would work together, rather they just look at the features individually and decide on a score. We have used approximate Shapley value, a concept of Coalition game theory, to deal with this problem. Further, in the case of a large dataset, it is important to work with shorter embeddings of the features. We have used CUR decomposition and Nystrom sampling to further reduce the feature space. To check the efficacy of this two-tier feature selection method, we have applied it to the features extracted by three standard deep learning models, namely VGG16, Xception and InceptionV3, where the features have been extracted from the CXR images of COVID-19 datasets and we have found that the selection procedure works quite well for the features extracted by Xception and InceptionV3. The source code of this work is available at https://github.com/subhankar01/covidfs-aihc.

TOPSIS aided ensemble of CNN models for screening COVID-19 in chest X-ray images.

The novel coronavirus (COVID-19), has undoubtedly imprinted our lives with its deadly impact. Early testing with isolation of the individual is the best possible way to curb the spread of this deadly virus. Computer aided diagnosis (CAD) provides an alternative and cheap option for screening of the said virus. In this paper, we propose a convolution neural network (CNN)-based CAD method for COVID-19 and pneumonia detection from chest X-ray images. We consider three input types for three identical base classifiers. To capture maximum possible complementary features, we consider the original RGB image, Red channel image and the original image stacked with Robert's edge information. After that we develop an ensemble strategy based on the technique for order preference by similarity to an ideal solution (TOPSIS) to aggregate the outcomes of base classifiers. The overall framework, called TOPCONet, is very light in comparison with standard CNN models in terms of the number of trainable parameters required. TOPCONet achieves state-of-the-art results when evaluated on the three publicly available datasets: (1) IEEE COVID-19 dataset + Kaggle Pneumonia Dataset, (2) Kaggle Radiography dataset and (3) COVIDx.

An adaptive and altruistic PSO-based deep feature selection method for Pneumonia detection from Chest X-rays.

Pneumonia is one of the major reasons for child mortality especially in income-deprived regions of the world. Although it can be detected and treated with very less sophisticated instruments and medication, Pneumonia detection still remains a major concern in developing countries. Computer-aided based diagnosis (CAD) systems can be used in such countries due to their lower operating costs than professional medical experts. In this paper, we propose a CAD system for Pneumonia detection from Chest X-rays, using the concepts of deep learning and a meta-heuristic algorithm. We first extract deep features from the pre-trained ResNet50, fine-tuned on a target Pneumonia dataset. Then, we propose a feature selection technique based on particle swarm optimization (PSO), which is modified using a memory-based adaptation parameter, and enriched by incorporating an altruistic behavior into the agents. We name our feature selection method as adaptive and altruistic PSO (AAPSO). The proposed method successfully eliminates non-informative features obtained from the ResNet50 model, thereby improving the Pneumonia detection ability of the overall framework. Extensive experimentation and thorough analysis on a publicly available Pneumonia dataset establish the superiority of the proposed method over several other frameworks used for Pneumonia detection. Apart from Pneumonia detection, AAPSO is further evaluated on some standard UCI datasets, gene expression datasets for cancer prediction and a COVID-19 prediction dataset. The overall results are satisfactory, thereby confirming the usefulness of AAPSO in dealing with varied real-life problems. The supporting source codes of this work can be found at https://github.com/rishavpramanik/AAPSO.

An agent-based transmission model of COVID-19 for re-opening policy design.

The global pandemic caused by the coronavirus (COVID-19) disease has collapsed the worldwide economy. Elements such as non-obligatory vaccination, new strain variants and lack of discipline to follow social distancing measures suggest the possibility that COVID-19 may continue to exist, exhibiting the behavior of a seasonal disease. As the socio-economic crisis has become unsustainable, all countries are planning strategies to gradually restart their economic and social activities. Initially, several containment measures have been adopted involving social distancing, infection detection tests, and ventilation systems. Despite the implementation of such policies, there exists a lack of evaluation of their performance to reduce the contagion index. This means there are no appropriate indicators to decide which intervention or set of interventions present the most effective result. Under these conditions, the development of models that provide useful information in the design and evaluation of containment measures and re-opening policies is of prime concern. In this paper, a novel approach to model the transmission process of COVID-19 in closed environments is proposed. The proposed model can simulate the effects that result from the complex interaction among individuals when they follow a particular containment measure or re-opening policy. With the proposed model, different hypothetical re-opening policies, that are otherwise impossible to analyze in real conditions, can be tested. Computer experiments demonstrate that the proposed model provides suitable information and realistic predictions, which are appropriate for designing strategies that allow a safe return to economic activities.

COVID-19 chest X-ray detection through blending ensemble of CNN snapshots.

The novel COVID-19 pandemic, has effectively turned out to be one of the deadliest events in modern history, with unprecedented loss of human life, major economic and financial setbacks and has set the entire world back quite a few decades. However, detection of the COVID-19 virus has become increasingly difficult due to the mutating nature of the virus, and the rise in asymptomatic cases. To counteract this and contribute to the research efforts for a more accurate screening of COVID-19, we have planned this work. Here, we have proposed an ensemble methodology for deep learning models to solve the task of COVID-19 detection from chest X-rays (CXRs) to assist Computer-Aided Detection (CADe) for medical practitioners. We leverage the strategy of transfer learning for Convolutional Neural Networks (CNNs), widely adopted in recent literature, and further propose an efficient ensemble network for their combination. The DenseNet-201 architecture has been trained only once to generate multiple snapshots, offering diverse information about the extracted features from CXRs. We follow the strategy of decision-level fusion to combine the decision scores using the blending algorithm through a Random Forest (RF) meta-learner. Experimental results confirm the efficacy of the proposed ensemble method, as shown through impressive results upon two open access COVID-19 CXR datasets - the largest COVID-X dataset, as well as a smaller scale dataset. On the large COVID-X dataset, the proposed model has achieved an accuracy score of 94.55% and on the smaller dataset by Chowdhury et al., the proposed model has achieved a 98.13% accuracy score.

CovidConvLSTM: A fuzzy ensemble model for COVID-19 detection from chest X-rays.

The rapid outbreak of COVID-19 has affected the lives and livelihoods of a large part of the society. Hence, to confine the rapid spread of this virus, early detection of COVID-19 is extremely important. One of the most common ways of detecting COVID-19 is by using chest X-ray images. In the literature, it is found that most of the research activities applied convolutional neural network (CNN) models where the features generated by the last convolutional layer were directly passed to the classification models. In this paper, convolutional long short-term memory (ConvLSTM) layer is used in order to encode the spatial dependency among the feature maps obtained from the last convolutional layer of the CNN and to improve the image representational capability of the model. Additionally, the squeeze-and-excitation (SE) block, a spatial attention mechanism, is used to allocate weights to important local features. These two mechanisms are employed on three popular CNN models - VGG19, InceptionV3, and MobileNet to improve their classification strength. Finally, the Sugeno fuzzy integral based ensemble method is used on these classifiers' outputs to enhance the detection accuracy further. For experiments, three chest X-ray datasets, which are very prevalent for COVID-19 detection, are considered. For all the three datasets, it is found that the results obtained by the proposed method are comparable to state-of-the-art methods. The code, along with the pre-trained models, can be found at https://github.com/colabpro123/CovidConvLSTM.

Binary Simulated Normal Distribution Optimizer for feature selection: Theory and application in COVID-19 datasets.

Classification accuracy achieved by a machine learning technique depends on the feature set used in the learning process. However, it is often found that all the features extracted by some means for a particular task do not contribute to the classification process. Feature selection (FS) is an imperative and challenging pre-processing technique that helps to discard the unnecessary and irrelevant features while reducing the computational time and space requirement and increasing the classification accuracy. Generalized Normal Distribution Optimizer (GNDO), a recently proposed meta-heuristic algorithm, can be used to solve any optimization problem. In this paper, a hybrid version of GNDO with Simulated Annealing (SA) called Binary Simulated Normal Distribution Optimizer (BSNDO) is proposed which uses SA as a local search to achieve higher classification accuracy. The proposed method is evaluated on 18 well-known UCI datasets and compared with its predecessor as well as some popular FS methods. Moreover, this method is tested on high dimensional microarray datasets to prove its worth in real-life datasets. On top of that, it is also applied to a COVID-19 dataset for classification purposes. The obtained results prove the usefulness of BSNDO as a FS method. The source code of this work is publicly available at https://github.com/ahmed-shameem/Feature_selection.

Inverted bell-curve-based ensemble of deep learning models for detection of COVID-19 from chest X-rays

Novel Coronavirus 2019 disease or COVID-19 is a viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The use of chest X-rays (CXRs) has become an important practice to assist in the diagnosis of COVID-19 as they can be used to detect the abnormalities developed in the infected patients’ lungs. With the fast spread of the disease, many researchers across the world are striving to use several deep learning-based systems to identify the COVID-19 from such CXR images. To this end, we propose an inverted bell-curve-based ensemble of deep learning models for the detection of COVID-19 from CXR images. We first use a selection of models pretrained on ImageNet dataset and use the concept of transfer learning to retrain them with CXR datasets. Then the trained models are combined with the proposed inverted bell curve weighted ensemble method, where the output of each classifier is assigned a weight, and the final prediction is done by performing a weighted average of those outputs. We evaluate the proposed method on two publicly available datasets: the COVID-19 Radiography Database and the IEEE COVID Chest X-ray Dataset. The accuracy, F1 score and the AUC ROC achieved by the proposed method are 99.66%, 99.75% and 99.99%, respectively, in the first dataset, and, 99.84%, 99.81% and 99.99%, respectively, in the other dataset. Experimental results ensure that the use of transfer learning-based models and their combination using the proposed ensemble method result in improved predictions of COVID-19 in CXRs.

MRFGRO: a hybrid meta-heuristic feature selection method for screening COVID-19 using deep features.

COVID-19 is a respiratory disease that causes infection in both lungs and the upper respiratory tract. The World Health Organization (WHO) has declared it a global pandemic because of its rapid spread across the globe. The most common way for COVID-19 diagnosis is real-time reverse transcription-polymerase chain reaction (RT-PCR) which takes a significant amount of time to get the result. Computer based medical image analysis is more beneficial for the diagnosis of such disease as it can give better results in less time. Computed Tomography (CT) scans are used to monitor lung diseases including COVID-19. In this work, a hybrid model for COVID-19 detection has developed which has two key stages. In the first stage, we have fine-tuned the parameters of the pre-trained convolutional neural networks (CNNs) to extract some features from the COVID-19 affected lungs. As pre-trained CNNs, we have used two standard CNNs namely, GoogleNet and ResNet18. Then, we have proposed a hybrid meta-heuristic feature selection (FS) algorithm, named as Manta Ray Foraging based Golden Ratio Optimizer (MRFGRO) to select the most significant feature subset. The proposed model is implemented over three publicly available datasets, namely, COVID-CT dataset, SARS-COV-2 dataset, and MOSMED dataset, and attains state-of-the-art classification accuracies of 99.15%, 99.42% and 95.57% respectively. Obtained results confirm that the proposed approach is quite efficient when compared to the local texture descriptors used for COVID-19 detection from chest CT-scan images.

COVID-19 detection from CT scans using a two-stage framework.

Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It may cause serious ailments in infected individuals and complications may lead to death. X-rays and Computed Tomography (CT) scans can be used for the diagnosis of the disease. In this context, various methods have been proposed for the detection of COVID-19 from radiological images. In this work, we propose an end-to-end framework consisting of deep feature extraction followed by feature selection (FS) for the detection of COVID-19 from CT scan images. For feature extraction, we utilize three deep learning based Convolutional Neural Networks (CNNs). For FS, we use a meta-heuristic optimization algorithm, Harmony Search (HS), combined with a local search method, Adaptive ß -Hill Climbing (A ß HC) for better performance. We evaluate the proposed approach on the SARS-COV-2 CT-Scan Dataset consisting of 2482 CT scan images and an updated version of the previous dataset containing 2926 CT scan images. For comparison, we use a few state-of-the-art optimization algorithms. The best accuracy scores obtained by the present approach are 97.30% and 98.87% respectively on the said datasets, which are better than many of the algorithms used for comparison. The performances are also at par with some recent works which use the same datasets. The codes for the FS algorithms are available at: https://github.com/khalid0007/Metaheuristic-Algorithms.

GraphCovidNet: A graph neural network based model for detecting COVID-19 from CT scans and X-rays of chest.

COVID-19, a viral infection originated from Wuhan, China has spread across the world and it has currently affected over 115 million people. Although vaccination process has already started, reaching sufficient availability will take time. Considering the impact of this widespread disease, many research attempts have been made by the computer scientists to screen the COVID-19 from Chest X-Rays (CXRs) or Computed Tomography (CT) scans. To this end, we have proposed GraphCovidNet, a Graph Isomorphic Network (GIN) based model which is used to detect COVID-19 from CT-scans and CXRs of the affected patients. Our proposed model only accepts input data in the form of graph as we follow a GIN based architecture. Initially, pre-processing is performed to convert an image data into an undirected graph to consider only the edges instead of the whole image. Our proposed GraphCovidNet model is evaluated on four standard datasets: SARS-COV-2 Ct-Scan dataset, COVID-CT dataset, combination of covid-chestxray-dataset, Chest X-Ray Images (Pneumonia) dataset and CMSC-678-ML-Project dataset. The model shows an impressive accuracy of 99% for all the datasets and its prediction capability becomes 100% accurate for the binary classification problem of detecting COVID-19 scans. Source code of this work can be found at GitHub-link .

Pneumonia detection in chest X-ray images using an ensemble of deep learning models.

Pneumonia is a respiratory infection caused by bacteria or viruses; it affects many individuals, especially in developing and underdeveloped nations, where high levels of pollution, unhygienic living conditions, and overcrowding are relatively common, together with inadequate medical infrastructure. Pneumonia causes pleural effusion, a condition in which fluids fill the lung, causing respiratory difficulty. Early diagnosis of pneumonia is crucial to ensure curative treatment and increase survival rates. Chest X-ray imaging is the most frequently used method for diagnosing pneumonia. However, the examination of chest X-rays is a challenging task and is prone to subjective variability. In this study, we developed a computer-aided diagnosis system for automatic pneumonia detection using chest X-ray images. We employed deep transfer learning to handle the scarcity of available data and designed an ensemble of three convolutional neural network models: GoogLeNet, ResNet-18, and DenseNet-121. A weighted average ensemble technique was adopted, wherein the weights assigned to the base learners were determined using a novel approach. The scores of four standard evaluation metrics, precision, recall, f1-score, and the area under the curve, are fused to form the weight vector, which in studies in the literature was frequently set experimentally, a method that is prone to error. The proposed approach was evaluated on two publicly available pneumonia X-ray datasets, provided by Kermany et al. and the Radiological Society of North America (RSNA), respectively, using a five-fold cross-validation scheme. The proposed method achieved accuracy rates of 98.81% and 86.85% and sensitivity rates of 98.80% and 87.02% on the Kermany and RSNA datasets, respectively. The results were superior to those of state-of-the-art methods and our method performed better than the widely used ensemble techniques. Statistical analyses on the datasets using McNemar's and ANOVA tests showed the robustness of the approach. The codes for the proposed work are available at https://github.com/Rohit-Kundu/Ensemble-Pneumonia-Detection.

COFE-Net: An ensemble strategy for Computer-Aided Detection for COVID-19.

Biomedical images contain a large volume of sensor measurements, which can reveal the descriptors of the disease under investigation. Computer-based analysis of such measurements helps detect the disease, and thereby swiftly aid medical professionals to choose adequate therapy. In this paper, we propose a robust deep learning ensemble framework known as COVID Fuzzy Ensemble Network, or COFE-Net. This strategy is proposed for the task of COVID-19 screening from chest X-rays (CXR) and CT Scans, as a part of Computer-Aided Detection (CADe) for medical practitioners. We leverage the strategy of Transfer Learning for Convolutional Neural Networks (CNNs) widely adopted in recent literature, and further propose an efficient ensemble network for their combination. The principles of fuzzy logic have been leveraged to combine the measured decision scores generated by three state-of-the-art CNNs - Inception V3, Inception ResNet V2 and DenseNet 201 - through the Choquet fuzzy integral. Experimental results support the efficacy of our approach over empirical ensembling, as the fuzzy ensembling strategy for biomedical measurement consists of dynamic refactoring of the classifier ensemble weights on the fly, based upon the confidence scores for coalitions of inputs. This is the chief advantage of our biomedical measurement strategy over others as other methods do not adjust to the multiple generated measurements dynamically unlike ours.Impressive results on multiple datasets demonstrate the effectiveness of the proposed method. The source code of our proposed method is made available at: https://github.com/theavicaster/covid-cade-ensemble.

COVID-19 detection from lung CT-Scans using a fuzzy integral-based CNN ensemble.

The COVID-19 pandemic has collapsed the public healthcare systems, along with severely damaging the economy of the world. The SARS-CoV-2 virus also known as the coronavirus, led to community spread, causing the death of more than a million people worldwide. The primary reason for the uncontrolled spread of the virus is the lack of provision for population-wise screening. The apparatus for RT-PCR based COVID-19 detection is scarce and the testing process takes 6-9 h. The test is also not satisfactorily sensitive (71% sensitive only). Hence, Computer-Aided Detection techniques based on deep learning methods can be used in such a scenario using other modalities like chest CT-scan images for more accurate and sensitive screening. In this paper, we propose a method that uses a Sugeno fuzzy integral ensemble of four pre-trained deep learning models, namely, VGG-11, GoogLeNet, SqueezeNet v1.1 and Wide ResNet-50-2, for classification of chest CT-scan images into COVID and Non-COVID categories. The proposed framework has been tested on a publicly available dataset for evaluation and it achieves 98.93% accuracy and 98.93% sensitivity on the same. The model outperforms state-of-the-art methods on the same dataset and proves to be a reliable COVID-19 detector. The relevant source codes for the proposed approach can be found at: https://github.com/Rohit-Kundu/Fuzzy-Integral-Covid-Detection.

Choquet Integral and Coalition Game-Based Ensemble of Deep Learning Models for COVID-19 Screening From Chest X-Ray Images.

Under the present circumstances, when we are still under the threat of different strains of coronavirus, and since the most widely used method for COVID-19 detection, RT-PCR is a tedious and time-consuming manual procedure with poor precision, the application of Artificial Intelligence (AI) and Computer-Aided Diagnosis (CAD) is inevitable. Though, some vaccines have now been authorized worldwide, it will take huge time to reach everyone, especially in developing countries. In this work, we have analyzed Chest X-ray (CXR) images for the detection of the coronavirus. The primary agenda of this proposed research study is to leverage the classification performance of the deep learning models using ensemble learning. Many papers have proposed different ensemble learning techniques in this field, some methods using aggregation functions like Weighted Arithmetic Mean (WAM) among others. However, none of these methods take into consideration the decisions that subsets of the classifiers take. In this paper, we have applied Choquet integral for ensemble and propose a novel method for the evaluation of fuzzy measures using coalition game theory, information theory, and Lambda fuzzy approximation. Three different sets of fuzzy measures are calculated using three different weighting schemes along with information theory and coalition game theory. Using these three sets of fuzzy measures, three Choquet integrals are calculated and their decisions are finally combined. Besides, we have created a database by combining several image repositories developed recently. Impressive results on the newly developed dataset and the challenging COVIDx dataset support the efficacy and robustness of the proposed method. Our experimental results outperform many recently proposed methods.

ET-NET: an ensemble of transfer learning models for prediction of COVID-19 infection through chest CT-scan images.

The COVID-19 virus has caused a worldwide pandemic, affecting numerous individuals and accounting for more than a million deaths. The countries of the world had to declare complete lockdown when the coronavirus led to community spread. Although the real-time Polymerase Chain Reaction (RT-PCR) test is the gold-standard test for COVID-19 screening, it is not satisfactorily accurate and sensitive. On the other hand, Computer Tomography (CT) scan images are much more sensitive and can be suitable for COVID-19 detection. To this end, in this paper, we develop a fully automated method for fast COVID-19 screening by using chest CT-scan images employing Deep Learning techniques. For this supervised image classification problem, a bootstrap aggregating or Bagging ensemble of three transfer learning models, namely, Inception v3, ResNet34 and DenseNet201, has been used to boost the performance of the individual models. The proposed framework, called ET-NET, has been evaluated on a publicly available dataset, achieving 97.81±0.53% accuracy, 97.77±0.58% precision, 97.81±0.52% sensitivity and 97.77±0.57% specificity on 5-fold cross-validation outperforming the state-of-the-art method on the same dataset by 1.56%. The relevant codes for the proposed approach are accessible in: https://github.com/Rohit-Kundu/ET-NET_Covid-Detection.

Prediction of COVID-19 from Chest CT Images Using an Ensemble of Deep Learning Models

The novel SARS-CoV-2 virus, responsible for the dangerous pneumonia-type disease, COVID-19, has undoubtedly changed the world by killing at least 3,900,000 people as of June 2021 and compromising the health of millions across the globe. Though the vaccination process has started, in developing countries such as India, the process has not been fully developed. Thereby, a diagnosis of COVID-19 can restrict its spreading and level the pestilence curve. As the quickest indicative choice, a computerized identification framework ought to be carried out to hinder COVID-19 from spreading more. Meanwhile, Computed Tomography (CT) imaging reveals that the attributes of these images for COVID-19 infected patients vary from healthy patients with or without other respiratory diseases, such as pneumonia. This study aims to establish an effective COVID-19 prediction model through chest CT images using efficient transfer learning (TL) models. Initially, we used three standard deep learning (DL) models, namely, VGG-16, ResNet50, and Xception, for the prediction of COVID-19. After that, we proposed a mechanism to combine the above-mentioned pre-trained models for the overall improvement of the prediction capability of the system. The proposed model provides 98.79% classification accuracy and a high F1-score of 0.99 on the publicly available SARS-CoV-2 CT dataset. The model proposed in this study is effective for the accurate screening of COVID-19 CT scans and, hence, can be a promising supplementary diagnostic tool for the forefront clinical specialists.